Extract from : Doctoring the Mind

For those readers who would like a more detailed outline of the contents of Doctoring the Mind I proceed as follows. In Chapter 1, I ask whether there is any evidence that psychiatry has made a positive impact on human welfare. Surprisingly, it seems that there is not. For example, whereas the recent history of physical medicine has been marked by dramatic breakthroughs, leading to measurable improvements in the likelihood of surviving life-threatening diseases, there is no evidence of similar advances in our ability to treat severe mental illness. This leads me to ask why psychiatry has failed when other branches of medicine have been so successful.

The historical section of the book, which occupies the next three chapters, explains how the current ineffective approach to psychiatric care has evolved. Whereas the historical chapters in Madness Explained focused exclusively on the development of theories of psychiatric classification, in this book I focus much more on the evolution of different kinds of psychiatric treatment. Of course, any history must be selective, emphasizing some events and neglecting others in an attempt to weave a coherent narrative. For obvious reasons, I have tried to provide an antidote to the kind of Whig history contained in books such as Michael Stone’s Healing the Mind,5 and Edward Shorter’s A History of Psychiatry which, despite having many strengths, inaccurately portray the glorious present as the culmination of centuries of steady scientific progress. Along the way, I consider the impact of the creation of the new profession of clinical psychology at the end of the Second World War, which has been completely overlooked by conventional histories. (A psychiatrist reviewing Madness Explained argued that naked professional rivalry had undermined its arguments. This observation made me think carefully about how I portrayed the relationship between clinical psychology and psychiatry in this book. However, in the end, it seemed to me that ideological and professional conflict between the two professions has been a historical reality and so I decided that it was pointless to pretend otherwise.) After describing how the discovery of chlorpromazine prompted renewed optimism in biomedical approaches to mental illness, I explain how the emergence of the new technologies of neuroimaging and molecular genetics has reinforced the modern view that psychiatric disorders are genetically determined brain diseases that must be treated with drugs.

The next three chapters deal with some myths about the nature of severe mental illness that underpin current psychiatric practice. Chapter 5 is the only chapter that overlaps considerably with Madness Explained, and considers the value of psychiatric diagnoses. In Chapter 6, I review what the current evidence tells us about the genetic and environmental determinants of psychosis, contrasting theories that locate the causes of illness within the person with those that locate them in the world. A particular target of my critique is the statistical measure of heritability, which is often cited by those who believe that psychiatric disorders are genetic diseases. This is probably the most technically demanding chapter in the book but I hope that I have explained the relevant concepts in a way that will be easily followed by the intelligent lay reader. In Chapter 7, I consider whether and to what extent psychiatric disorders can be said to be caused by brain disease. It turns out that this question is much more easily addressed if we attempt to explain particular kinds of complaints (symptoms) such as hallucinations and delusions, rather than meaningless diagnostic categories such as ‘schizophrenia’. The picture that emerges is much more consistent with the idea that severe mental illnesses are influenced by the social environment, than with the idea that they are genetically determined disorders of the brain.

The following three chapters consider the effectiveness of modern psychiatric therapies. I begin by describing the emergence of the evidence-based medicine movement, which has led to widespread faith in the randomized controlled trial (RCT) as a measure of treatment effectiveness. Focusing on antidepressants, I show how the pharmaceutical industry has systematically distorted RCT data to promulgate a wildly over-optimistic impression of what psychiatric drugs can do. In Chapter 9, I extend this analysis by showing that the evidence in favour of antipsychotic drugs is much less compelling than is usually supposed, and that psychiatrists have been blinded to the adverse effects of these drugs in much the same way that they were blind to the effects of the crude brain operations and other extreme remedies used in the middle years of the twentieth century. Unfortunately, as we discover in Chapter 10, this does not mean that drug therapies can be entirely replaced by psychological treatments. Although the last decade has shown growing enthusiasm for one particular type of psychological treatment for severe mental illness – cognitive behaviour therapy (CBT) – the evidence that any one type of therapy is better than any other is by no means clear-cut. This observation provokes two kinds of responses. Some hard-line biological psychiatrists have concluded that CBT is just some form of elaborate placebo but a better conclusion is that it is the quality of the therapeutic relationship that determines outcome. Hence, by paying attention to this relationship, and placing it at the centre of psychiatric practice, we can see a way to develop services that are more humane and effective. As much as psychiatric services today are an improvement on those of the past, it is because they are kinder and more respectful of the needs of patients, rather than because of the availability of new therapies.

This conclusion leads me to the last chapter, in which I address what is to be done to improve psychiatric services in the future. It will be no surprise that I think that they need to be much less medically orientated, but perhaps a disappointment to some of my colleagues that I do not see the solution as a full-scale takeover bid by Clinical Psychology Inc. Indeed, I argue that it is the engagement of patients in the design and development of services that is most likely to lead to lasting improvements.